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Recent research has shown small, non-coding microRNAs to be master regulators of cellular processes, and expression patterns have revealed their potential as diagnostic, prognostic, and treatment response biomarkers. Cambridge Healthtech Institute’s Twelfth Annual microRNA as Biomarkers and Diagnostics meeting will cover the latest research in the use of microRNAs for early detection of disease, monitoring cancer progression and therapeutic response, and understanding immunity. Implications for the future of personalized medicine will also be discussed.  

Coverage Includes:

  • Circulating microRNAs as diagnostic and predictive biomarkers
  • Tissue-based microRNA biomarkers
  • Role of microRNAs in metastasis and tumor growth
  • Predicting and monitoring response to therapy
  • Monitoring disease progression
  • microRNA biomarkers of drug toxicity
  • microRNAs in immune response
  • Challenges of NGS


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Extracellular RNAs (exRNAs) found in biofluids are a rich source of information about cellular processes in both health and disease. In particular, exRNAs enclosed in extracellular vesicles and therefore protected from degradation, are involved in intercellular communication and may serve as diagnostic and prognostic biomarkers of cancer, cardiovascular and neurodegenerative diseases. Cambridge Healthtech Institute’s Second Annual Extracellular RNA in Drug and Diagnostic Development meeting will present the latest research in this emerging area of non-invasive diagnostics, including exosomes and microvesicles, circulating microRNA and other non-coding RNA, and issues of standardization, profiling, and data analysis.

Coverage includes:

  • exRNAs in liquid biopsy
  • exRNA profiles associated with cardiovascular and neurodegenerative diseases
  • exRNAs for cancer diagnosis and prognosis
  • Circulating extracellular microRNA and lncRNA
  • Cell-to-cell communication
  • Exosomes and microvesicles
  • Development of an exRNA Atlas
  • Standardization issues
  • Challenges of data analysis

Presenting Research Updates from the NIH Extracellular RNA Communication Consortium

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